Question

Which of the following is a valid limitation of Koch's Postulates?

पर्याय

• The postulates require the use of living animals in all cases

• The postulates cannot be tested where no susceptible animal model exists

• The postulates require the disease to spread to multiple hosts

• The postulates are only applicable to bacterial infections

Answer 1

One significant limitation of Koch's Postulates is that they cannot be tested in situations where no susceptible animal model exists. For human-specific diseases or diseases that only occur in certain species, researchers may not have an appropriate model organism to use in the third postulate, making complete verification of causation impossible.