Question

What is the significance of pedigree analysis for the geneticist? Give one example where it can be been used for genetic counselling.

Answer 1

Pedigree analysis helps identify whether a trait is dominant, recessive, autosomal or sex-linked, and allows likely genotypes and inheritance risks to be estimated. For example, a couple with a family history of sickle-cell anaemia can be counselled about the possibility of having an affected child.