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प्रश्न
How does colchicine act as mitotic poison? Is there any advantage of it?
टीपा लिहा
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उत्तर
Colchicine is an alkaloid obtained from Autumn crocus (Colchicum autumnale). It inhibits the formation of mitotic spindle. As a result, chromosomes duplicate but they remain within the same cell, increasing in number (endoduplication). Such cells are called polyploid cells.
Its advantage is that plant breeders have used colchicine-induced polyploidy as a means of producing variants of agricultural and horticultural crops.
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