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प्रश्न
Assertion: In sickle cell anaemia, the codon GAG is replaced by GUG.
Reason: The gene for the above mutation occurs on the Y-chromosome.
पर्याय
Both assertion and reason are true, and reason is the correct explanation of the assertion.
Both assertion and reason are true, but reason is not the correct explanation of assertion.
Assertion is true but reason is false.
Both assertion and reason are false.
MCQ
विधान आणि तर्क
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उत्तर
Assertion is true but reason is false.
Explanation:
In sickle cell anaemia, the codon GAG is indeed replaced by GUG causing substitution of glutamic acid by valine in the β-globin chain. However, this gene mutation is on an autosome, not on the Y-chromosome; sickle cell anaemia is autosomal recessive, affecting both sexes equally.
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