Definitions [13]
Define the following.
Pathogen
A pathogen is a biological agent that causes disease to its host. e.g. bacteria, virus, etc.
Define the following:
Disease
Disease:
The disease can be defined as an impairment or malfunctioning of the normal state of the living organism that disturbs or modifies the performance of vital functions of the body.
Any deviation from normal state of health is called disease.
A disease caused by a specific pathogenic organism and capable of being transmitted to another individual by direct or indirect contact is known as communicable (infectious) disease.
Define the following: Droplet infection
Droplet infection is an infection transmitted from one individual to another by droplets of saliva or nasal moisture during coughing, sneezing, speaking and spitting.
Define the following: Vector
A vector is an organism that carries disease causing microbes (pathogens) from one host to another. They are the carriers of infection.
Example: Mosquito, housefly, etc
Define the following: Infectious diseases
The diseases which spread from an infected person to a healthy person through air, water, food, soil or physical contact are called communicable diseases.
Example : Common cold, chickenpox, etc
Define the following: Pathogen
The microbes that cause disease are called pathogens.
Example : Bacteria, virus, etc
The process of administering a vaccine to stimulate the immune system and provide protection against infectious diseases is called vaccination.
Define the following:
Infection
Infection is the entry, development, or multiplication of an infectious agent in the human body or animals.
Define the following.
Vaccines
Preparation of antigenic proteins of pathogens (weakened or killed) which on inoculation into a healthy person provides temporary/permanent immunity against a particular disease.
Define the following:
Antibiotics
Antibiotics are metabolic products of microorganisms whose very low concentrations are inhibitory or detrimental to other microbes.
A preparation containing specific antigens that is administered to induce temporary or permanent immunity against a particular disease is called a vaccine.
Key Points
- Principle: Works on the immune system's memory. A vaccine (weakened/inactivated pathogen or its proteins) stimulates antibody production and generates memory B and T-cells.
- On Re-exposure: Memory cells quickly recognise the pathogen and produce massive antibodies to neutralise it.
- Passive Immunisation: Preformed antibodies/antitoxins are directly injected when quick response is needed (e.g., tetanus, snakebite).
- Types of Vaccines: Protein/sugar from pathogen, dead/inactivated pathogen, toxoid, or attenuated (weakened) pathogen.
- Recombinant DNA Vaccines: Antigenic polypeptides produced in bacteria/yeast for large-scale production (e.g., Hepatitis B vaccine from yeast).
