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प्रश्न
Answer the following question.
Two children, A and B aged 4 and 5 years respectively visited a hospital with a similar genetic disorder. The girl A was provided enzyme-replacement therapy and was advised to revisit periodically for further treatment. The girl, B was, however, given a therapy that did not require revisit for further treatment.
Why did the treatment provided to girl A required repeated visits?
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उत्तर
Girl A was given Enzyme replacement therapy in which lymphocytes isolated from patient's blood are cultured in-vitro. Functional ADA cDNA is then introduced into the cultured lymphocytes. These lymphocytes are returned back to the patient's body. Lymphocytes are not immortal. Therefore, repeated infusion of genetically engineered lymphocytes is required and hence it is not a permanent treatment and the patient has to revisit periodically in the future.
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संबंधित प्रश्न
How sex is determined in monoecious plants. write their genes involved in it.
Haploid plants are preferred over diploids for mutation study because in haploids ______.
Rate of mutation is affected by ______.
Which one of the following is a sort of chromosomal aberration?
A change of single base pair in the gene for beta-globin chain (in human haemoglobin) results in the change of amino acid residue glutamic acid to valine which is due to ______
Mutations result in
Variations caused due to mutations are ______.
Match list I with list II
| List I | List II | ||
| A. | A pair of chromosomes extra with diploid | i) | monosomy |
| B. | One chromosome extra to the diploid | ii) | tetrasomy |
| C. | One chromosome was lost from diploid | iii) | trisomy |
| D. | Two individual chromosomes lose from diploid | iv) | double monosomy |
Match list I with list II.
| List I | List II |
| A. A pair of chromosomes extra with diploid | i) monosomy |
| B. One chromosome extra to the diploid | ii) tetrasomy |
| C. One chromosome loses from diploid | iii) trisomy |
| D. Two individual chromosomes lose from diploid | iv) double monosomy |
Match list I with list II.
| List I | List II | ||
| A. | A pair of chromosomes extra with diploid | i) | monosomy |
| B. | One chromosome extra to the diploid | ii) | tetrasomy |
| C. | One chromosome loses from diploid | iii) | trisomy |
| D. | Two individual chromosomes lose from diploid | iv) | double monosomy |
