Share

# Unit Operations 2 Semester 4 (SE Second Year) BE Biotechnology University of Mumbai Topics and Syllabus

SubjectUnit Operations 2
CBCGS [2017 - current]
CBGS [2013 - 2016]
Old [2000 - 2012]

## Topics with syllabus and resources

100.00 Introduction
• Various modes of heat transfer Viz. Conduction, Convection and Radiation.
200.00 Conduction
• Fouriers law
• Steady state unidirectional heat flow through single and multiple layer slabs
• Cylinders and spheres for constant and variable thermal conductivity.
300.00 Insulation
• Properties of insulation materials
• Types of insulation
• Critical and Optimum thickness of insulation.
400.00 Extended Surfaces
1. Fins
• Types of fins
• Derivation of fin efficiency for longitudinal fins
• Fin effectiveness.
• Elementary treatment of unsteady state heat conduction.
• Problems
500.00 Convection
• Individual and overall heat transfer coefficient, LMTD, LMTD correction factor.
• Dimensionless numbers
• Dimensional analysis
• Empirical correlation for forced and natural convection.
• Analogy between momentum and heat transfer – Reynolds, Coulburn and Prandtl analogies.
• Problems
600.00 Heat Transfer with Phase Change
• Boiling phenomena, Nucleate and film boiling
• Condensation – Film and Drop wise condensation, Nusselts equations.
• Properties and definitions
• Absorptivity
• Reflectivity
• Emissive power and intensity of radiation
• Stefen – Boltzmann law, Wien’s displacement law, Kirchoffs law, View factors
• Radiation between surfaces- different shapes
• Radiation involving gases and vapours
800.00 Heat Transfer Equipment
• Double pipe heat exchangers
• Shell and tube heat exchangers – Types of shell and tube heat exchangers
• Condenser – types of condensers.
• Design of heat exchanger.
900.00 Evaporators
• Types of evaporators
• performance of tubular evaporator – Evaporator capacity, Evaporator economy, Multiple effect evaporator.
1000.00 Diffusion
• Molecular diffusion in fluids
• Diffusion coefficient
• Flick’s Law of diffusion
• Dependence of diffusion coefficient on temperature, pressure and composition
• Diffusion in multi-component gas mixtures.
• Diffusion in solids:- Molecular, Knudsen & surface diffusion Inter- phase mass transfer, Mass transfer coefficients
• Diffusion between phases
• Equilibrium solubility of gases in liquids
• Mass Transfer theories
• Mass transfer in fluidized beds, flow past solids and boundary layers
• Simultaneous heat and mass transfer.
1100.00 Mass Transfer in Bioprocess Operations
• Role of Diffusion in Bioprocessing
• Oxygen Uptake in Cell Culture
• Factors affecting cellular oxygen demand
• oxygen transfer from gas bubble to cell
• oxygen transfer in fermenters
• sparging stirring and medium properties
• anti foaming agents
• temperature
• gas pressure and oxygen partial pressure
• presence of cells
• measuring dissolved oxygen concentration
• estimating oxygen solubility
• effect of oxygen partial pressure
• effect of temperature
• effect of solutes
• mass transfer correlations
• measurement of kLa
• oxygen balance method
• dynamic method
• sulphite oxidation method
• oxygen transfer in large vessels.
1200.00 Distillation
• simple, steam & equilibrium distillation
• fractionation.
• MccabeThiele method
• azeotropes
• numericals.
S