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Unit Operations 2 Semester 4 (SE Second Year) BE Biotechnology University of Mumbai Topics and Syllabus

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CBCGS [2017 - current]
CBGS [2013 - 2016]
Old [2000 - 2012]

Topics with syllabus and resources

100.00 Introduction
  • Various modes of heat transfer Viz. Conduction, Convection and Radiation.
200.00 Conduction
  • Fouriers law
  • Steady state unidirectional heat flow through single and multiple layer slabs
  • Cylinders and spheres for constant and variable thermal conductivity.
300.00 Insulation
  • Properties of insulation materials
  • Types of insulation
  • Critical and Optimum thickness of insulation.
400.00 Extended Surfaces
  1. Fins
  • Types of fins
  • Derivation of fin efficiency for longitudinal fins
  • Fin effectiveness.
  • Elementary treatment of unsteady state heat conduction.
  • Problems
500.00 Convection
  • Individual and overall heat transfer coefficient, LMTD, LMTD correction factor.
  • Dimensionless numbers
  • Dimensional analysis
  • Empirical correlation for forced and natural convection.
  • Analogy between momentum and heat transfer – Reynolds, Coulburn and Prandtl analogies.
  • Problems
600.00 Heat Transfer with Phase Change
  • Boiling phenomena, Nucleate and film boiling
  • Condensation – Film and Drop wise condensation, Nusselts equations.
700.00 Radiation
  • Properties and definitions
  • Absorptivity
  • Reflectivity
  • Emissive power and intensity of radiation
  • Black body radiation
  • Gray body radiation
  • Stefen – Boltzmann law, Wien’s displacement law, Kirchoffs law, View factors
  • Radiation between surfaces- different shapes
  • Radiation involving gases and vapours
  • Radiation shields.
800.00 Heat Transfer Equipment
  • Double pipe heat exchangers
  • Shell and tube heat exchangers – Types of shell and tube heat exchangers
  • Condenser – types of condensers.
  • Design of heat exchanger.
900.00 Evaporators
  • Types of evaporators
  • performance of tubular evaporator – Evaporator capacity, Evaporator economy, Multiple effect evaporator.
1000.00 Diffusion
  • Molecular diffusion in fluids
  • Diffusion coefficient
  • Flick’s Law of diffusion
  • Dependence of diffusion coefficient on temperature, pressure and composition
  • Diffusion in multi-component gas mixtures.
  • Diffusion in solids:- Molecular, Knudsen & surface diffusion Inter- phase mass transfer, Mass transfer coefficients
  • Diffusion between phases
  • Equilibrium solubility of gases in liquids
  • Mass Transfer theories
  • Mass transfer in fluidized beds, flow past solids and boundary layers
  • Simultaneous heat and mass transfer.
1100.00 Mass Transfer in Bioprocess Operations
  • Role of Diffusion in Bioprocessing
  • Oxygen Uptake in Cell Culture
  • Factors affecting cellular oxygen demand
  • oxygen transfer from gas bubble to cell
  • oxygen transfer in fermenters
  • sparging stirring and medium properties
  • anti foaming agents
  • temperature
  • gas pressure and oxygen partial pressure
  • presence of cells
  • measuring dissolved oxygen concentration
  • estimating oxygen solubility
  • effect of oxygen partial pressure
  • effect of temperature
  • effect of solutes
  • mass transfer correlations
  • measurement of kLa
  • oxygen balance method
  • dynamic method
  • sulphite oxidation method
  • oxygen transfer in large vessels.
1200.00 Distillation
  • simple, steam & equilibrium distillation
  • fractionation.
  • MccabeThiele method
  • azeotropes
  • numericals.
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