CBCGS [2019 - current]
CBGS [2015 - 2018]
Old [2000 - 2014]
University of Mumbai Semester 8 (BE Fourth Year) Bioseparation and Downstream Processing Technology 2 Revised Syllabus
University of Mumbai Semester 8 (BE Fourth Year) Bioseparation and Downstream Processing Technology 2 and their Unit wise marks distribution
Units and Topics
| # | Unit/Topic | Marks |
|---|---|---|
| 100 | Adsorption and Ion Exchange | - |
| 200 | Membrane Separation Techniques | - |
| 300 | Equipments for Gas-liquid Contacting Applicable for Bioprocesses | - |
| 400 | Crystallization | - |
| 500 | Drying | - |
| 600 | Case Studies of Downstream Processing | - |
| Total | - |
Syllabus
100 Adsorption and Ion Exchange
- Introduction to Adsorption
- Types of Adsorption:- Adsorption Isotherms, Single Stage Adsorption, Multistage Cross Current Adsorption, Multistage Counter Current Adsorption
- Equipments for Adsorption Ion Exchange Equilibria, Ion Exchange Equipments Design and Construction of Chromatographic Columns for Bioseparations
200 Membrane Separation Techniques
- Membrane separation processes: Reverse Osmosis, Ultrafiltration, Microfiltration, Nanofiltration, Dialysis, Electrodialysis, Gas Permeation, Pervaporation
- Types of Membranes, Membrane Modules and design Retention coefficient, Concentration Polarization, Membrane fouling
- Factors affecting membrane filtration
- Advantages of membrane separation processes over conventional separation techniques
- Industrial Applications
300 Equipments for Gas-liquid Contacting Applicable for Bioprocesses
- Classification of equipments for gas-liquid contacting, Gas dispersed and liquid continuous phase- Sparged Vessels (Bubble Columns), Mechanically Agitated Vessels, Tray Towers, Spray Towers and Spray Chambers, Packed Towers
- Comparison of Packed Towers with Tray Towers.
400 Crystallization
- Solubility curve, Super saturation, Method of obtaining super saturation
- Effect of heat on size and growth of crystal, Rate of Crystal growth and Delta-L law of crystal growth, Material and energy balance for crystallizers
- Crystallization equipment-description
500 Drying
- Introduction to drying, Equilibrium, Different types of moisture contents, Rate of Drying and drying curve, Batch Drying and calculation of time of drying, types of driers
- Lyophilization
- Formulation
600 Case Studies of Downstream Processing
- Baker’s yeast, Ethanol, Citric acid, Penicillin, Insulin, interferon, Monoclonal antibodies, Tissue plasminogen activator, Taq polymerase
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