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Biological Modeling and Simulation Semester 6 (TE Third Year) BE Biomedical Engineering University of Mumbai Topics and Syllabus

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CBCGS [2018 - current]
CBGS [2014 - 2017]
Old [2000 - 2013]

University of Mumbai Semester 6 (TE Third Year) Biological Modeling and Simulation Revised Syllabus

University of Mumbai Semester 6 (TE Third Year) Biological Modeling and Simulation and their Unit wise marks distribution

Units and Topics

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Syllabus

100 Physiological Modeling
  • Steps in Modeling
  • Purpose of Modeling
  • Lumped parameter models
  • Distributed parameter models
  • Compartmental modeling
  • Modeling of circulatory system
  • Regulation of cardiac output and respiratory system.
200 Model of Neurons
  • Biophysics tools
  • Nernst Equation
  • Donnan Equilibrium
  • Active Transport ( Pump) GHK equation
  • Action Potential
  • Voltage Clamp
  • Channel Characteristics
  • Hodgkin- Huxley Conductance Equations
  • Simulation of action potential
  • Electrical Equivalent model of a biological membrane
  • Impulse propagation- core conductor model , cable equations.
300 Neuromuscular System
  • Modeling of skeletal muscle
  • Mono and polysynaptic reflexes
  • Stretch reflex
  • Reciprocal innervations
  • Two control mechanism
  • Golgi tendon
  • Experimental validation
  • Parkinson’s syndrome.
400 Eye Movement Model
  • Four eye movements
  • Quantitative eye movement models
  • Validity criteria.
500 Thermo Regulatory Systems
  • Thermoregulatory mechanisms
  • Model of thermoregulatory system
  • Controller model
  • Validation and application.
600 Modelling of Other Physiological Systems
  • Modelling the Immune response: Behavior of the immune system, linearized model of the immune response.
  • Modelling of Drug delivery systems.
  • Modelling of Insulin Glucose feedback system and Pulsatile Insulin secretion.
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