BE Biotechnology Semester 6 (TE Third Year)University of Mumbai
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Bioinformatics 2 Semester 6 (TE Third Year) BE Biotechnology University of Mumbai Topics and Syllabus

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CBCGS [2018 - current]
CBGS [2014 - 2017]
Old [2000 - 2013]

Topics with syllabus and resources

100.00 Introduction to Concepts of Molecular Modelling
  1. Methods of molecular modelling:- Molecular mechanics, Abinitio Quantum mechanics, Semi empirical quantum mechanics
  2. Energy minimization of molecules: local & global energy minima.
200.00 Interactions
  • Protein ligand interactions
  • Torsion angle
  • Ramchandran plot
  • Protein folding & Chaperones
  • Cartesian coordidates
300.00 Overview, Interoperability and Interexchange Languages
  1. Overview: Machine learning, Genetic algorithms, Simulated annealing.
  2. Interoperability: Introduction, Its role in bioinformatics.
  3. Interexchange Languages: XML, CORBA, And UMLS. Clustering algorithms.
400.00 Drug Designing
  • Drug optimization
  • Identification of pharmacophore
  • Optimizing access to target
  • Prodrugs
  • Endogenous compounds as drugs
  • Quantitative structure- activity relationship (QSAR)
500.00 Docking
  • Introduction
  • Protein protein docking
  • Protein Ligand docking
  • Applications of docking
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