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Why is it not possible for an alien DNA to become part of a chromosome anywhere along its length and replicate normally? - Biology

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Why is it not possible for an alien DNA to become part of a chromosome anywhere along its length and replicate normally?

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Solution

It is not possible for an alien DNA to become part of a chromosome anywhere along its length and replicate normally because the replication process begins at a particular spot called the origin of replication. Also, replication in eukaryotes occurs in the nucleus during the S phase of the cell cycle when the chromosomes are in their extended form.

Concept: DNA Replication - The Experimental Proof
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