What is the difference between native protein and denatured protein?
In a biological system, a protein is found to have a unique 3-dimensional structure and a protein with unique biological activity is called a native protein. However, when the native protein is subjected to physical or chemical changes, its hydrogen bonds are disturbed. This disturbance unfolds the globules and uncoils the helix. As a result, the protein loses its biological activity. This type of protein is called a denatured protein