Illustrate with examples the limitations of Williamson synthesis for the preparation of certain types of ethers.
The reaction of Williamson synthesis involves SN2 attack of an alkoxide ion on a primary alkyl halide.
But if secondary or tertiary alkyl halides are taken in place of primary alkyl halides, then elimination would compete over substitution. As a result, alkenes would be produced. This is because alkoxides are nucleophiles as well as strong bases. Hence, they react with alkyl halides, which results in an elimination reaction.
Solution for question: Illustrate with Examples the Limitations of Williamson Synthesis for the Preparation of Certain Types of Ethers. concept: Preparation of Ethers from Dehydration of Alcohols and Williamson Systhesis. For the courses PUC Karnataka Science, CBSE (Science)