Differentiate between Glycolysis and Krebs’cycle
|1||It occur inside the cytoplasm||Kreb's cycle operates inside mitochondria|
|2||Gyycolysis is the first step of respiration in which glucose is broken down to the level of pyruvate||Kreb's cycle is the second step in respiration where an active acetyl group is broken down completely|
|3||The process is common to both aerobic and anaerobic mode of respiration.||It occur only in aerobic respiration|
|4||It degrades a molecule of glucose into two molecules of an organic substance, pyruvate||It degrades pyruvate completely into organic substance (CO2 + H2O)|
|5||Glycolysis consume 2 ATP molecules for the initial phosphorylation of substrate molecule||It does not consume ATP|
|6||In glycolysis one gulcose molecule liberates 4 ATP molecules through substate level phosphorylation||In Kreb's cycle, two acetly residues liberate two ATP or GTP molecules through substrate level phosphorylation|
|7||Net gain is two molecule of NADH and two moleucles of ATP for every molecule of glucose broken down||Krebs'cycle produce six molecules of NADH and 2 molecules of FADH2 for every two molecule of acetyl CoA oxidised by it. Two molecules of NADH are liberated during conversion of two pyruvates to acetyl CoA.|
|8||The net gain of energy is equal to 8 ATP||The net gain of energy is equal to 24 molecules of ATP. Six molecules of ATP can be produced from 2NADH2 formed during dehydrogenation of two pyruvates.|
|9||No carbon dioxide is evolved in glycolsis||Carbon dioxide is evolved in Krebs cycle|
|10||Oxygen is not required for glycolysis||Krebs cycle uses oxygen as terminal oxidant|
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Solution Differentiate Between Glycolysis and Krebs’Cycle Concept: Glycolysis.