Arrange the compounds of each set in order of reactivity towards SN2 displacement:
2-Bromo-2-methylbutane, 1-Bromopentane, 2-Bromopentane
An SN2 reaction involves the approaching of the nucleophile to the carbon atom to which the leaving group is attached. When the nucleophile is sterically hindered, then the reactivity towards SN2 displacement decreases. Due to the presence of substituents, hindrance to the approaching nucleophile increases in the following order.
1-Bromopentane < 2-bromopentane < 2-Bromo-2-methylbutane
Hence, the increasing order of reactivity towards SN2 displacement is:
2-Bromo-2-methylbutane < 2-Bromopentane < 1-Bromopentane
Video Tutorials For All Subjects
- Chemical Reactions of Haloalkanes and Haloarenes - Reactions of Haloalkanes - Nucleophilic Substitution Reactions